Periapical Cyst (Radicular Cyst)

Periapical Cyst Or Radicular Cyst

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What Are We Talking About?

How many times, Doctor, has a patient presented to your clinic for root canal treatment, and upon taking a pre-operative X-ray, you discover a large, dark circular area surrounding the apex of the root? What’s the first thing that crosses your mind? Is this simply a periapical granuloma, or has the situation escalated into a full-blown cyst?

This radiographic presentation is among the most common we encounter daily. Today, we’ll delve into the details of the most prevalent type of inflammatory cyst in the jaws: the Radicular Cyst.

What Exactly Is a Periapical Cyst?

Simply put, Doctor, this is an inflammatory cyst that forms around the apex of a tooth’s root or, less commonly, at the opening of a lateral canal of a non-vital tooth. It’s considered a type of rarefying osteitis, and typically, we start classifying it as a cyst once its size exceeds 1 centimeter.

How It Appears on X-rays: Radiographic Features

To easily identify it on radiographs, you need to focus on these specific details:

Location

The most common location by far is the apex of a tooth. Occasionally, though not frequently, you might find it on the lateral aspect of a tooth, which usually indicates the presence of a lateral canal.

Edge

Its borders are consistently well-defined. Sometimes, these borders are outlined by a thin, radiopaque line, appearing corticated, while other times they aren’t. This cortication can actually disappear if the cyst becomes secondarily inflamed.

Shape

Its shape typically ranges from round to ovoid.

Internal Composition

Internally, it appears completely radiolucent on X-rays. It’s characteristically a single, unilocular chamber.

Number

Most commonly, it presents as a single cyst. However, it’s quite possible to find multiple cysts in different locations within the jaws.

How to Diagnose It Correctly: Key Diagnostic Signs

You will identify a radiolucent lesion that is unequivocally associated with a non-vital tooth.
Its size generally exceeds 1 centimeter.
It may cause displacement or resorption of adjacent structures, such as adjacent tooth roots.

Why It Matters: Clinical Significance

Its presence is a clear indicator of long-standing pulpal necrosis. If it grows considerably, it can lead to bone expansion. Treatment typically involves endodontic therapy for the affected tooth or its extraction, followed by the actual cyst enucleation. Accurate diagnosis here is paramount to formulating the most appropriate treatment plan.

A Very Important Diagnostic Point

Be aware, Doctor, differentiating between a periapical cyst and a periapical granuloma can be exceedingly challenging based on radiographs alone. While a size exceeding 1 centimeter strongly suggests a radicular cyst, the definitive diagnosis ultimately requires a histopathological examination. The most critical diagnostic clue guiding you is that the associated tooth will always be non-vital.

Share this topic with your colleagues and anyone you think could benefit.

Interested in learning more? Check out the references!

  1. Whaites, E., & Drage, N. (2021). Essentials of Dental Radiography and Radiology.

  2. White, S.C., & Pharoah, M.J. (2014). Oral Radiology: Principles and Interpretation.

  3. Neville, B.W., Damm, D.D., Allen, C.M., & Chi, A.C. (2015). Oral and Maxillofacial Pathology.

  4. Radiopaedia.org. (2025). Radicular cyst. Radiopaedia.org.

  5. Khademi, A. (2013). Radicular Cyst. IntechOpen.

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